Kamano pakeng tsa Liprotheine, Peptides, le Amino Acids
Liprotheine: Li-macromolecules tse sebetsang tse entsoeng ke ketane e le 'ngoe kapa ho feta tsa polypeptide tse phuthehang ka har'a meaho e itseng ea mahlakore a mararo ka liheli, lishiti, joalo-joalo.
Liketane tsa Polypeptide: Limolek'hule tse kang ketane tse entsoeng ka li-amino acid tse peli kapa ho feta tse hokahantsoeng ke litlamo tsa peptide.
Amino Acids: Mehaho ea motheo ea liprotheine; mefuta e fetang 20 e teng ka tlhaho.
Ka kakaretso, liprotheine li entsoe ka liketane tsa polypeptide, tseo le tsona li entsoeng ka li-amino acid.
Ts'ebetso ea Ts'ilo ea Liprotheine le ho Monya ho Liphoofolo
Oral Pre-atreatment: Lijo li robeha 'meleng ka ho hlafuna ka hanong, ho eketsa sebaka se ka holimo bakeng sa tšilo ea enzymatic. Kaha molomo o haelloa ke li-enzyme tse silang lijo, mohato ona o nkoa e le tšilo ea lijo ka mochine.
Karohano ea Pele ka Mpeng:
Kamora hore liprotheine tse arohaneng li kene ka mpeng, asiti ea gastric e a li hlahisa, e pepesa litlamo tsa peptide. Pepsin ebe e pshatla liprotheine ka mokhoa oa enzymatic ho li-polypeptide tse kholo tsa molek'hule, tseo hamorao li kenang ka maleng a manyane.
Tšilo ea lijo ka Malang a Manyenyane: Trypsin le chymotrypsin ka maleng a manyenyane li tsoela pele ho senya li-polypeptides ho li-peptide tse nyenyane (dipeptides kapa tripeptides) le amino acid. Tsena li kenngoa ka har'a lisele tsa mala ka litsamaiso tsa lipalangoang tsa amino acid kapa sistimi e nyane ea lipalangoang tsa peptide.
Phepong ea liphoofolo, likarolo tse peli tsa protheine-chelated trace elements le li-trace elements tse nyane tsa peptide-chelated li ntlafatsa bioavailability ea trace elements ka chelation, empa li fapana haholo mekhoeng ea tsona ea ho monya, botsitso le maemo a sebetsang. Lintlha tse latelang li fana ka tlhahlobo ea papiso ho tsoa likarolong tse 'nè: mochine oa ho monya, litšoaneleho tsa sebopeho, liphello tsa ts'ebeliso, le maemo a loketseng.
1. Mokhoa oa ho monya:
| Papiso Pontshi | Protheine-chelated Trace Elements | Lisebelisoa tse nyane tsa Peptide-chelated Trace |
|---|---|---|
| Tlhaloso | Li-chelate li sebelisa liprotheine tsa macromolecular (mohlala, protheine ea semela ea hydrolyzed, whey protein) joalo ka bajari. Li-ion tsa tšepe (mohlala, Fe²⁺, Zn²⁺) li theha maqhama a ho hokahanya le lihlopha tsa carboxyl (-COOH) le amino (-NH₂) tsa masalla a amino acid. | E sebelisa li-peptide tse nyane (tse entsoeng ka 2-3 amino acid) joalo ka bajari. Li-ion tsa tšepe li theha li-chelate tse tsitsitseng tse nang le litho tse hlano kapa tse tšeletseng tse nang le lihlopha tsa amino, lihlopha tsa carboxyl le lihlopha tsa ketane ea mahlakoreng. |
| Mokhoa oa ho monya | E hloka ho senyeha ha liprotheine (mohlala, trypsin) ka maleng hore e be li-peptide tse nyane kapa li-amino acid, tse lokollang li-ion tsa tšepe tse chelated. Li-ion tsena li kena maling ka ho hasana kapa ho tsamaisoa ka mafolofolo ka likanale tsa ion (mohlala, DMT1, ZIP/ZnT li-transporters) liseleng tsa mala a epithelial. | E ka monngoa e le li-chelates tse sa tsitsang ka kotloloho ka sepalangoang sa peptide (PepT1) liseleng tsa mala a epithelial. Ka har'a sele, li-ion tsa tšepe li lokolloa ke li-enzyme tsa intracellular. |
| Mefokolo | Haeba ts'ebetso ea li-enzyme tsa tšilo ea lijo e sa lekana (mohlala, ho liphoofolo tse nyane kapa tlas'a khatello ea maikutlo), katleho ea ho senyeha ha protheine e tlase. Sena se ka lebisa ho ferekanngoa pele ho nako ea mohaho oa chelate, ho lumella li-ion tsa tšepe hore li tlameletsoe ke lintho tse khahlanong le phepo e nepahetseng joaloka phytate, ho fokotsa tšebeliso. | Thibelo ea tlholisano ea mala a bypasses (mohlala, ho tsoa ho phytic acid), le ho monya ha hoa itšetleha ka ts'ebetso ea enzyme ea tšilo ea lijo. Haholo-holo e loketse liphoofolo tse nyenyane tse nang le mekhoa e sa tloaelehang ea ho senya lijo kapa liphoofolo tse kulang / tse fokolang. |
2. Litšobotsi tsa Sebopeho le Botsitso:
| Sebopeho | Protheine-chelated Trace Elements | Lisebelisoa tse nyane tsa Peptide-chelated Trace |
|---|---|---|
| Boima ba Molek'hule | E kholo (5,000~20,000 Da) | Nyenyane (200~500 Da) |
| Chelate Bond Matla | Multiple coordinate bonds, empa ho rarahana ha molek'hule ho lebisa ho botsitso bo itekanetseng ka kakaretso. | Khokahano e bonolo ea peptide e khuts'oane e lumella hore ho thehoe mehaho ea mehele e tsitsitseng haholoanyane. |
| Bokhoni ba ho thibela ho kena-kenana | E ka susumetsoa ke asiti ea gastric le ho feto-fetoha ha pH ea mala. | asiti e matla le ho hanyetsa alkali; botsitso bo phahameng sebakeng sa mala. |
3. Liphello tsa Ts'ebeliso:
| Sesupo | Liprotheine tsa Chelates | Li-Chelates tse nyane tsa Peptide |
|---|---|---|
| Bioavailability | E itšetlehile ka ts'ebetso ea enzyme ea tšilo ea lijo. E sebetsa hantle ho liphoofolo tse kholo tse phetseng hantle, empa katleho e fokotseha haholo ho liphoofolo tse nyane kapa tse imetsoeng kelellong. | Ka lebaka la tsela e tobileng ea ho monya le sebopeho se tsitsitseng, trace element bioavailability ke 10% ~ 30% e phahameng ho feta ea protheine chelates. |
| Katoloso ea Ts'ebetso | Ts'ebetso e fokolang haholo, e sebetsa joalo ka trace element carriers. | Li-peptide tse nyane ka botsona li na le mesebetsi e kang taolo ea 'mele ea ho itšireletsa mafung le ts'ebetso ea antioxidant, e fanang ka litlamorao tse matla tsa synergistic tse nang le likarolo tsa mohlala (mohlala, Selenomethionine peptide e fana ka tlatsetso ea selenium le mesebetsi ea antioxidant). |
4. Maemo a Loketseng le Maikutlo a Moruo:
| Sesupo | Protheine-chelated Trace Elements | Lisebelisoa tse nyane tsa Peptide-chelated Trace |
|---|---|---|
| Liphoofolo Tse Loketseng | Liphoofolo tse kholo tse phelang hantle (mohlala, likolobe tse qetellang, likhoho tse behelang) | Liphoofolo tse nyenyane, liphoofolo tse tlas'a khatello ea kelello, mefuta e mengata ea metsing e fanang ka lihlahisoa tse ngata |
| Litšenyehelo | Tlase (lisebelisoa tse tala li fumaneha habonolo, ts'ebetso e bonolo) | E phahameng (litšenyehelo tse phahameng tsa motsoako o monyane oa peptide le tlhoekiso) |
| Tšusumetso ea Tikoloho | Likarolo tse sa monngoeng li ka ’na tsa ntšoa mantleng, e leng se ka ’nang sa silafatsa tikoloho. | Sekhahla se phahameng sa tšebeliso, kotsi e tlase ea tšilafalo ea tikoloho. |
Kakaretso:
(1) Bakeng sa liphoofolo tse nang le litlhoko tse phahameng tsa trace element le matla a fokolang a tšilo ea lijo (mohlala, likolobe, litsuonyana, li-shrimp larvae), kapa liphoofolo tse hlokang ho lokisoa ka potlako ha mefokolo, li-chelate tse nyane tsa peptide li khothaletsoa e le khetho ea mantlha.
(2) Bakeng sa lihlopha tse sa tsotelleng litšenyehelo tse nang le ts'ebetso e tloaelehileng ea tšilo ea lijo (mohlala, mehlape le likhoho nakong ea ho qetela ea ho qetela), likarolo tsa protheine-chelated trace li ka khethoa.
Nako ea poso: Nov-14-2025
