Tšebeliso ea Hydroxy Methionine Copper 1

Lisebelisoa tsa Sehlahisoa

1) Li-broiler

Ha li-MMHAC (chelate ea hydroxy methionine ea koporo, zinki, le manganese) di ekeditswe dijong tsa di-broiler, diphetho di bontshitse hore—ha ho bapiswa le diminerale tsa setso tse sa tlwaelehang—ho kenyeletswa ha di-MMHAC ho ekeditse boima ba mmele le boima ba mesifa ya drumstick (serope) haholo, ho ntlafaditse ho sila ha koporo, mme ha ho a ka ha ba le ditlamorao tse mpe bophelong ba gizzard kapa masapo.

Tafole ea 1. Boima ba ho sebetsana le setopo (g/nonyana) le palo ea matsoele a masoeu a matsoele a fepuoang ka mokhoa oa inorganic le methionine hydroxyl analogue kalafo ea lijo ea chelated zinc, koporo le manganese sat letsatsi la 42.

Ntho	ITM	M10	T125	M30	SEM	Boleng ba P
Letswele	684	716	719	713	14.86	0.415
Serope	397	413	412	425	7.29	0.078
Moqomo	320	335	332	340	4.68	0.058
Serope le molamu	717 a	748 ab	745 ab	765 b	11.32	0.050
Sebaka sa mafura	32.3	33.1	33.4	35.5	1.59	0.546
Sebete	68.0	67.4	66.0	71.1	2.41	0.528
Pelo	18.8	18.6	19.2	19.2	0.68	0.898
Liphio	9.49	10.2	10.6	10.6	0.51	0.413

Hlokomela: ITM: Diminerale tse sa pheleng tse sa pheleng 110 ppm Zn as ZnSO4 16 ppm Cu as CuSO4 le120 ppm Mn as MnO ka Ross 308 dikgothaletso tsa phepo;

M10: Bongata ba 40 ppm Zn 10 ppm Cu le 40 ppm Mn e le chelate;

T125: Diminerale tse sa pheleng tse nang le manyolo 110 ppm Zn jwalo ka ZnSO4 le 120 ppm Mn jwalo ka MnO ka Ross 308 ditataiso tse nang le 125 ppm Cu jwalo ka tribasic copper chloride (TBCC);

M30 = 40 ppm Zn, 30 ppm Cu, le 40 ppm Mn e le chelate. Boleng bo moleng o le mong bo nang le di-superscript tse fapaneng bo fapana haholo (P < 0.05).

2) Likolobe

Phuputso e batlisisitse liphello tsa ho nkela liminerale tse sa tloaelehang sebaka ka karolo e itseng ka minerale ea methionine hydroxy analogue chelates (MMHAC) lijong tsa likolobe tse tšehali le likolobe tse nyane tsa tsona sebaka. Liphetho li bontšitse hore tlatsetso ea MMHAC e fokolitse tahlehelo ea boima ba 'mele ho likolobe tse tšehali tse anyesang, e khothalelitse keketseho ea boima ba 'mele ba likolobe tse nyane letsatsing la 18, e ntlafalitse haholo maemo a acetylation ea mesifa ea masapo ha li tsoaloa, 'me e fokotsa tlhahiso ea liphatsa tse ngata tse amanang le ho ruruha le nts'etsopele ea mesifa. Ka kakaretso, MMHAC e ntlafalitse bophelo bo botle ba mala le nts'etsopele ea mesifa ho likolobe tse nyane ka taolo ea epigenetic le nts'etsopele, e ntlafatsa bokhoni ba tsona ba kholo.

Tafole ea 2 Litlamorao tse tlatsetsang tsa chelate ea minerale ea methionine hydroxy analogue lijong tsa kolobe mabapi le tlhahiso ea mRNA ea bohlokoa e amanang le ho ruruha ha jejunal ho kolobe e anyesang.

Ntho	ITM	CTM	SEM	P- boleng
d 1 ea ho anyesa x 10^-5
IL-8	1344	1018	178	0.193
MUC2	5380	5511	984	0.925
NF-κB (leq. 50)	701	693	93	0.944
NF-κB (leq. 105)	1991	1646	211	0.274
TGF-b1	Ho tloha ka 1991	1600	370	0.500
TNF-α	11	7	2	0.174
d 18 ea ho anyesa x 10^-5
IL-8	1134	787	220	0.262
MUC2	5773	3871	722	0.077

Hlokomela: Interleukin-8 (IL-8), mucin-2 (MUC2), nuclear factor-κB (NF-κB), transforming growth factor-1 (TGF-1), le tumor necrosis factor-α (TNF-α)

ITM = mehlodi e tloaelehileng ea liminerale tse sa tloaelehang (boemo ba ho kenyelletsoa ha 0.2% lijong)

CTM = 50:50 mineral methionine hydroxy analogue chelate le minerale tse sa pheleng (boemo ba ho kenyelletsoa ha 0.2% lijong)

3)Li-buminant

Ha ho anyesa likhomo tsa lebese, ho nkela halofo ea sulfate ea koporo sebaka kahydroxy methionine koporoho ekelitse haholo mahloriso a koporo maling, ho ntlafalitse ho sila ha faeba e sa nke lehlakore ea sesepa sa ho hlatsoa (NDF) le faeba e hloekisang asiti (ADF), le ho ntlafatsa tlhahiso ea lebese le tlhahiso ea lebese e lokisitsoeng ka mafura ka 4%. Liphuputso tsena li bontša hore ho nkela koporo sulfate sebaka ka karolo e itseng ka (HMTBA)₂-Cu lijong tsa likhomo tsa lebese ke leano le sebetsang hantle la phepo.

Tafole ea 3 Litlamorao tsa methionine hydroxy Cu [(HMTBA)2-Cu] holim'a motsoako oa lebese la likhomo

Ntho	S	SM	M	SEM	Boleng ba P
DMI, kg/ka letsatsi	19.2	20.3	19.8	0.35	0.23
Palo ea lebese, kg/ka letsatsi	28.8	33.8	31.3	1.06	0.08
Mafura, %	3.81	3.74	3.75	0.06	0.81
Protheine, %	3.34	3.28	3.28	0.04	0.19
Lactose, %	4.48	4.35	4.43	0.05	0.08
SNF, %	8.63	8.84	8.63	0.05	0.33
Tekanyo ea mafura, kg/d	1.04	1.22	1.10	0.04	0.09
Poelo ea protheine, kg/d	0.92	0.92	0.90	0.03	0.72
Kotulo ea lactose, kg/ka letsatsi	1.23	1.23	1.21	0.04	0.45
Urea N, mg/dL	18.39	17.70	18.83	0.45	0.19
4% FCM, kg/ka letsatsi	26.1	30.1	27.5	0.91	0.06

Kalafo: S = Cu sulfate feela: 12 mg ea Cu e fanoeng ke CuSO4 ka kilogram ea concentrate; SM = Cu sulfate le (HMTBA)2-Cu: 6 mg ea Cu e fanoeng ke CuSO4, le 6 mg e 'ngoe ea Cu e fanoeng ke (HMTBA)2-Cu ka kilogram ea concentrate; M = (HMTBA)2-Cu feela: 12 mg ea Cu e fanoeng ke (HMTBA)2-Cu ka kilogram ea concentrate.